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Regenerative Injection Therapies

Regenerative Injection Therapies

Pain and inflammation are wiped out—and degeneration is halted and even reversed—when Dr. LaBeau uses injections of medical grade ozone, growth factors, and nutrients to stimulate tissue healing.

PROLOTHERAPY

Prolotherapy (Proliferative Therapy) is a recognized Non-Surgical orthopedic procedure that stimulates the body’s healing processes to strengthen and repair injured and painful joints and connective tissue. Prolotherapy has the ability to address the cause of the instability, repair the weakened sites and produce new collagen tissue, resulting in permanent stabilization of the joint. Anti-inflammatory or other pain relievers only act temporarily & surgery is more risky and fails to stabilize the joint and relieve pain.

The original and most commonly used form of Prolotherapy consisting of Procaine and a Dextrose solution (D50W).

PROLOZONE THERAPY (Hi Octane Prolotherapy)

PROLOZONE therapy is a second generation Prolotherapy consisting of Procaine, Colloidal Silver, Methyl B12, and Homeopathic anti-inflammatory solution along with Ozone.

Like Prolotherapy, Prolozone Therapy is designed to cause moderately severe pain lasting typically 12 to 24 hours.  You are to avoid Aspirin and other anti-inflammatory medications, like Ibuprofen.  Dr. LaBeau prescribes pain medication like Vicodin, if desired, which does not interfere with the healing process.

Dr. LaBeau will typically initially recommend a trial of 4-6 injections done 2-4 weeks apart.  Typically, multiple points, tailored to the individual, are injected in an area such as a joint or area of the back for optimal results.  Up to 2 areas of the body can be done at a time, but a longer office visit is required when injecting to areas.  To further facilitate healing Dr. LaBeau also recommends myo-fascial soft tissue therapy to be done throughout the treatment process.

In fact, with each injection the natural healing process continues for the next 6-8 weeks just like with an injury.  With each injection there is a cumulative effect!

NEWBORN GROWTH FACTORS  (Beyond Stem Cells)

THE CONTROVERSY

When it comes to Regenerative therapy who hasn’t heard of Stem Cell Therapy?  Then next, there is the ongoing academic and ethical debate between the use of Adult vs Fetal stem cells.  The solution? Newborn Growth Factors derived from mothers undergoing scheduled C-Sections. This provides all the benefits of a newborn without the ethical controversy.

THE SCIENCE

Further studies have  shown that your own stem cells are stimulated to contribute to the healing process stimulated by Newborn Growth Factors.  Therefore, these Growth Factors have  the “Punch” of newborns vigor regulating your own stem cells to regenerate damaged tissue! 

THE PROCEDURE

Newborn Growth Factors Therapy may cause mild to moderate pain at the site of injection.  You are to avoid Aspirin and other anti-inflammatory medications, like Ibuprofen.

Dr. LaBeau prescribes pain medication like Tramadol for short term use (1-2 days). It does not interfere with the healing process.

Dr. LaBeau typically recommends 1 to 2 injections depending on the patient’s response. Injections are given 3 months apart. Typically, a single point, tailored to the individual, is injected in an area such as a joint or area of the back for optimal results.  Up to 2 different areas of the body can be done at a time.  To further facilitate healing Dr. LaBeau also recommends myo-fascial soft tissue therapy to be done throughout the treatment process every 2 weeks to maximally enhance the healing process.

In patients that get only a partial response with the 1st injection Dr. LaBeau will decide if it would be beneficial to use a larger dose of Newborn Growth Factors or add another agent such as Ozone to the injection.

THE CONCLUSION

Significant pain reduction is common within the 1st week after injection. However, healing continues for the next 8 to 12 weeks. 

Prolotherapy -Questions & Answers

WHAT IS PROLOTHERAPY?

Prolotherapy works by stimulating the body’s release of Growth Factors which are powerful hormone like proteins that repair and lay down new tissue in the weakened area. This is done by a specifically directed injection to the injury site, stimulating the body to go into a reparative mode. The inflammatory response which is created by the injection encourages growth of new, normal ligament or tendon fibers, resulting in a tightening of the weakened structure. Additional treatments repeat this process, allowing a gradual buildup of tissue to restore the original strength to the area.

HOW DOES PROLOTHERAPY WORK?

Prolotherapy injections contain natural substances that stimulate the production of Growth Factors that create a healing response, as well as local anesthetic agents to help with the pain of the injection. Traditional formulas include ingredients such as dextrose, saline, sarapin, or pumice along with either procaine or lidocaine. In the last several years newer formulas include Sodium Morrhuate from fish oil, Colloidal Silver, Vitamins, and Homeopathic solutions.  Each treating physician tailors the selection of the appropriate formula according to the patient’s need.

WHAT IS THE SOLUTION THAT IS INJECTED?

Areas/problems treated include: Low back or mid-back pain including degenerative disc disease and sacro-iliac joint instability/dysfunctionneck painknee pain, knee meniscal tearswrist or hand pain, osteoarthritis, shoulder pain including rotator cuff tears, elbow pain including golfers or tennis elbowfoot pain including plantar fasciitis, ankle pain or instability, hypermobility, osteitis pubis, IT band syndrome, piriformis syndrome, temporal mandibular joint syndrome (TMJ), or other musculoskeletal pain or injury. Some areas or problems can be more challenging than others, and it is therefore important to be evaluated by a physician trained and experienced in this procedure so that an accurate assessment and treatment plan can be given.

IS PROLOTHERAPY TREATMENT PAINFUL?

Any pain involving an injection will vary according to the structure or joint treated, the choice of solution, and the skill of the physician administering the injection. The treatment results in moderately-severe pain with mild swelling and stiffness lasting 12-48 hours. The discomfort usually passes fairly quickly and can also be reduced with pain relievers such as Tylenol or other prescribed medication depending on your pain thresholdAnti-inflammatory drugs, such as aspirin and ibuprofen, are not recommended for pain relief because their action suppresses the desired inflammatory healing process produced by the Prolotherapy injections.

CAN PROLOTHERAPY HELP EVERYONE?

Each patient must be evaluated thoroughly with patient history, physical exam and radiological or ultrasound exam. When indicated, laboratory work, should be ordered or evaluated prior to treatment. With this information, your physician can evaluate your potential success with this therapy. Success depends on factors which include the history of damage to the patient, the patient’s overall health and ability to heal, and any underlying nutritional or other deficiencies that would impede the healing process. In appropriate patients, Prolotherapy has a high success rate.

WHAT AREAS OF THE BODY CAN BE TREATED?

Areas/problems treated include: Low back or mid-back pain including degenerative disc disease and sacro-iliac joint instability/dysfunctionneck painknee pain, knee meniscal tearswrist or hand pain, osteoarthritis, shoulder pain including rotator cuff tears, elbow pain including golfers or tennis elbowfoot pain including plantar fasciitis, ankle pain or instability, hypermobility, osteitis pubis, IT band syndrome, piriformis syndrome, temporal mandibular joint syndrome (TMJ), or other musculoskeletal pain or injury. Some areas or problems can be more challenging than others, and it is therefore important to be evaluated by a physician trained and experienced in this procedure so that an accurate assessment and treatment plan can be given.

HOW OFTEN DO I NEED THESE TREATMENTS?

Treatment intervals vary depending on the specific problem and severity of the area being treated, as well as the protocol of the physician. Typical intervals between treatments are every two to six weeks, with an average interval of once a monthfor a total of four to six treatments. However this can vary and may be more frequent, or take longer, depending on the condition being treated.

WHAT'S THE SUCCESS IN TREATMENT FOR PROLOTHERAPY?

The anticipated rate of success depends on a number of variables, including the patient’s history and ability to heal, and the type of solution used. In patients with low back pain, studies have shown a 70% to 85% of patients experience improvement with Prolotherapy (compared to studies showing a 52% improvement with back surgery). Many research studies done over the years show a high success rate when Prolotherapy is used for various ligament, tendon or joint pain/injuries.

HOW LONG HAS PROLOTHERAPY BEEN ARROUND?

Prolotherapy/sclerotherapy has been used successfully as early as 500 B.C. when Roman soldiers with shoulder joint dislocations were treated with hot branding irons to help fuse the torn ligaments in the shoulder joint. Advances in medicines greatly improved on this process, and led to the modern techniques of strengthening the fibrous tissue and creating new, normal collagen, rather than producing scarring to fuse tissues.

Hippocrates described vein sclerotherapy around 400 B.C. using “slender instruments of iron” to treat varicose veins. Injection sclerotherapy of veins was first reported in 1623 while modern forms of injection sclerotherapy for varicose veins, hernias and hemorrhoids has been performed since the early 1900’s.

Earl Gedney, D.O., a well-known Orthopedist, decreased his surgical practice and began to inject joints in the 1940s and 1950s, and spent the rest of his life researching and publishing on the subject. Also, George Hackett, M.D., wrote a book on this injection therapy, with Gustav Hemwall MD adding to that publication in the 1950’s. Both Gedney and Hackett’s work is still used today in training physicians. In the years since this early work, techniques and medications have advanced to move from a scarring or fusing effect to a strengthening, regenerative effect, which restores the weakened joint to its original level of stability, without loss of flexibility and function.

HOW IS PROLOTHERAPY RELATED TO PROLOZONE, PRP, STEM CELLS OR NEWBORN GROWTH FACTORS?

Advances in Regenerative Medicine have made the use of more advanced formulas possible for even more enhanced healing. Ozone added to the Prolotherapy cocktail known as Prolozone therapy adds to the inflammatory stimulation of Growth Factors as well as being anti-microbial which effectively benefit infected joints. Platelet Rich Plasma (PRP) derived from the patient’s own blood provides available circulating Plasma cells and Growth Factors to enhance healing. Stem Cells derived from either one’s bone or fatty tissue can directly repair damaged tissue, but healing can be limited do the current level of one’s own health. Newborn Growth Factors on the other hand have the potential of providing a robust level of healing being obtained from healthy women undergoing a scheduled C-Section.

WHAT IS PROLOZONE THERAPY?

Prolozone Therapy is a technique that combines the principles of neural therapy, Prolotherapy, and ozone therapy. It involves injecting combinations of procaine, anti-inflammatory medications, homeopathics, vitamins, minerals, proliferatives, and ozone/oxygen gas into degenerated or injured joints, and into areas of pain.

WHAT IS NEWBORN GROWTH FACTOR THERAPY?

The goals of Prolotherapy and Prolozone are to stimulate the body to heal through the release of Growth Factors.  Of course, limiting factors are: 1) the actual ability of the body to produce Growth Factors, 2) the overall health of the individual, 3) the limitations of circulation at the site of injury, and 4) the age and vitality of the individual.  The use of Newborn Growth Factors effectively deals with all these limitations by providing over 226 growth factors, cytokines, and regulatory proteins that together contribute to full spectrum healing to the sight of injury.

WHAT CAN YOU EXPECT AFTER YOUR INJECTION? - PROLOZONE

The first 45-60 minutes after an injection you may feel a sense of fullness and there may be some slushy noises in the joint. It is important to keep some gentle motion in the joint for the first hour without excessive stress on the joint.  Avoid any regular exercise for the next 72 hours to allow for healing.

During the first 24-48 hours you may experience moderate-severe pain in the area of injection. This will best be controlled with the application of ice at the injection site for 15 minutes. Alternating applications of ice and heat may also help.Avoid   use of over the counter non-steroidal anti-inflammatory drugs such as (ibuprofen, naproxen-sodium, aspirin or acetaminophen) use of these products will inhibit the healing process that the inflammation promotes.

After 24 hours, joint support with such agents as Glucosamine, MSM, and Turmeric are important to take during the injection process to control inflammation naturally as well as promote and maintain healthy connective tissue. Increasing intake of Vitamin C 1000-3,000 mg is also recommended for collagen support.

Most people will experience some reduction in pain, an improvement in stability and increased range of motion in the first 48 hours. During the first week some discomfort may return this is normal and is likely due to increased motion and use.

Dr. LaBeau will typically initially recommend a trial of 2-4 injections done 2-4 weeks apart.  Typically, multiple points, tailored to the individual, are injected in an area such as a joint or area of the back for optimal results.  Up to 2 areas of the body can be done at a time, but a longer office visit is required when injecting two areas.

It is vital to your success that recommendations concerning activity levels recommended by Dr. LaBeau are adhered to. Improper or over strenuous activity may inhibit the healing process or result in re-injury. Please remember your body is in the healing phase it is not yet completely healed.  In fact, with each injection the natural healing process continues for the next 6-8 weeks just like with an injury.  With each injection there is a cumulative effect!

WHAT CAN YOU EXPECT AFTER YOUR INJECTION? - NEWBORN GROWTH FACTORS

The first 45-60 minutes after an injection you may feel a sense of discomfort at the site of injection. It is important to keep some gentle motion in the joint for the first hour without excessive stress on the joint.  Avoid any regular exercise for the next 72 hours to allow for healing.

During the first 24-48 hours you may experience moderate-severe pain in the area of injection. This will best be controlled with the application of ice at the injection site for 15 minutes. Alternating applications of ice and heat may also help.Avoid   use of over the counter non-steroidal anti-inflammatory drugs such as (ibuprofen, naproxen-sodium, aspirin or acetaminophen) use of these products will inhibit the healing process that the inflammation promotes.

After 24 hours, joint support with such agents as Glucosamine, MSM, and Turmeric are important to take during the injection process to control inflammation naturally as well as promote and maintain healthy connective tissue. Increasing intake of Vitamin C 1000-3,000 mg is also recommended for collagen support.

Most people will experience some reduction in pain, an improvement in stability and increased range of motion in the first 48 hours. During the first week some discomfort may return this is normal and is likely due to increased motion and use.

Dr. LaBeau will typically initially recommend a trial of 1-2 injections done 3 months apart.  Typically, one or more points, tailored to the individual, are injected in an area such as a joint or area of the back for optimal results.  Up to 2 areas of the body can be done at a time, but a longer office visit is required when injecting two areas.

AminoFix is the Newborn Growth Factors we use and has been found to be 90% effective in reducing if not eliminating pain and inflammation.  If a patient is having a partial response to the AmnioFix then there is a better chance they will respond to a 2nd injection.

It is vital to your success that recommendations concerning activity levels recommended by Dr. LaBeau are adhered to. Improper or over strenuous activity may inhibit the healing process or result in re-injury. Please remember your body is in the healing phase it is not yet completely healed.  In fact, with the AminoFix  injection the natural healing process continues for the next 8-12 weeks just like with an injury.


Regenerative Injection Therapies are available at the Stengler Center for Integrative Medicine in San Diego.

Call today to schedule a consultation: 760-274-2377