Natural Hormone Replacement Therapy
Today millions of men and women worried about aging and maintaining a quality of life are undergoing hormone replacement therapy (HRT). Hormone-related problems- such as mood swings, PMS, infertility, endometriosis, fibrocystic breasts, weight gain, low sex drive, vaginal dryness, frequent bladder infection, cardiovascular disease, and osteoporosis-- can be relieved by achieving a proper hormone balance. In considering the benefit risk ratio, it is important to take into account alternatives to traditional therapy.
Why Natural Hormone Replacement Therapy?
Alternatives to conventional HRT include using natural plant-derived bio-identical hormones which have the same chemical makeup as those produced by the body. Synthetic hormones and hormones from animal sources do not allow the body to produce the full range of other hormones which are required to operate at full capacity, and thus are more likely to produce side effects.
If you haven't heard much about natural hormone replacement, you're not the only one. Because natural hormones can not be patented for the same reason you can not patent natural air, water, or vitamins, there's little or no incentive for the pharmaceutical industry to invest millions of dollars to develop, test, and submit to the FDA for approval, and market these hormones.
What hormones are we referring to?
Natural hormone replacement isn't just estrogens and progesterone. Natural estrogens and progesterone are just part of a complicated and closely interlinked hormone system that includes a lot of other hormones such as testosterone, DHEA, pregnenolone, and melatonin, to name just a few. Many of these hormones have been found to decrease with age. Restoring them to normal levels with natural replacement versions can have a remarkably revitalizing effect on our hearts and immune systems to our moods, energy, and sex drive.
Natural Estrogens
Estrogen is not one hormone, but a set of similar hormones with varying levels of activity. The three most vital estrogens are estrone, estradiol, and estriol. Estradiol is the primary estrogen produced by the ovary, and estrone is formed by the conversion of estradiol. The most popular kind of estrogen replacement continues to be conjugated estrogens (containing many estrogens that are natural to horses, but few that are natural to humans). In the intestinal tract, these are converted mostly to estrone. Synthetic Ethinyl estradiol is also frequently used in estrogen supplements. Estrone and estradiol are the estrogens primarily linked to breast and endometrial cancer.
New regimens have been developed that use natural estriol in the greatest concentration along with other naturally occurring estrogens in an appropriately balanced ratio. Estriol produces very little endometrial proliferation and rarely causes postmenopausal vaginal bleeding. Estriol may also be effective at lowering the risk of blood clots in the veins or lungs. Estriol is made in very large quantities during pregnancy and is believed to be protective against breast cancer. High levels of estriol are found in vegetarians and Asian women, who have a much lower risk of breast cancer.
Natural Progesterone
The hormone progesterone participates in practically every physiological process, in both men and women. The stabilizing action of progesterone is especially noticeable in muscle tissue, such as the uterus, blood vessel walls, the heart, the intestine, the bladder, and bone cells. Less noticeably, progesterone stabilizes and normalizes nervous, secretory, immune and growth processes.
Natural progesterone comes from yams and soybean. It matches precisely the chemical structure of the body's progesterone. Synthetic progesterone, or progestins, are chemically formulated from progesterone and react differently in the body causing unwanted side effects such as salt buildup, fluid retention, low blood sugar, breast tenderness, weight gain, and depression. The role of natural progesterone in preventing and treating osteoporosis, helping to clear endometriosis and fibrocystic breast, and treating vaginal dryness, infertility, and menstrual abnormalities is getting significant attention in the medical and lay communities. In men over 55 natural progesterone is being used to enhance libido, as well to treat osteoporosis.
Natural Androgens
In some cases, it is necessary to take into consideration the addition of androgens, testosterone or synthetic methyltestosterone, to a woman's hormone replacement regimen. Usually thought of as a male hormone, testosterone is also made by the female ovaries and is essential to normal sexual development. Testosterone plays an important part in maintaining sexual desire, as well as the strength and integrity of skin, muscle and bone, reducing cholesterol levels, and improving cardiovascular circulation in both men and women.
As a woman enters the transition of menopause, circulating androgens start to decline as a result of age-related decreases in adrenal and ovarian secretion. After menopause, a woman's overall androgen production decreases by as much as 50%. It is possible to supplement a woman's testosterone deficiency with the same natural testosterone she has produced most of her life. Synthetic hormones with even the smallest changes can produce side effects not found with the natural hormone.
DHEA, Pregnenolone, and Melatonin
Not just estrogen, progesterone, and testosterone, but a lot of other hormones, including growth hormone, melatonin, DHEA, and pregnenolone, reach peak levels before or during the third decade of life and then begin a steady decline of about 2% each year. Research clearly indicates that substituting inadequate levels of these vital hormones can, among other positive effects, help protect the heart, improve mental alertness, make bones stronger, and restore a lagging sex life. We are just starting to know the health benefits that can be attained by restoring levels of these essential hormones to their youthful peak.
Hormone Testing
Since steroid hormones play such an important role in the maintenance of health, knowledge of an imbalance in any one or more hormones can help illuminate the reason for health problems and supply a logical basis for correcting the imbalance through diet, exercise, or hormone supplementation.
Steroid hormone levels can be measured with blood and saliva testing. When the different glands produce the steroids they are released into the bloodstream bound to carrier proteins. Only a small portion (1-5%) of a given amount of steroid hormone breaks loose from the carrier protein in the bloodstream and is able to enter target tissues. Blood testing measures both the bound and unbound steroid hormones. Studies show that there is a strong connection between the levels of steroid hormones in the saliva and the bioavailable (unbound) levels of steroids in the bloodstream.
Levels of all steroid hormones can be determined individually by both blood and saliva testing. Blood testing requires a prescription from your physician. Saliva testing kits can be obtained through compounding pharmacies involved with natural hormone replacement.
Customize, Don't Compromise
As many as two-thirds of women that start HRT stop within two years. One main reason they quit is because of side effects, especially the irregular bleeding that can last anywhere from a few months to a few years.
So how do you get the benefits of HRT and bypass the side effects? Customize. HRT has to be carefully initiated by your doctor after a personal history, family history, and current medical situation are assessed. Everyone is unique and will respond to therapy in their own way: therefore the selection of hormone(s), dose, and dosage form should be specific to each person. Close observation is important to guarantee correct dosage changes and prevent unnecessary side effects. Compounding pharmacists can make natural hormones in a variety of doses, regimens, and preparations developed to make you more comfortable with your therapy while gaining long-term benefits.
For further information about Dr. Stengler’s practice and his clinic in Leucadia, California, please visit our website at MarkStengler.com or give us a call at (760) 274-2377
